The green synthesis of 2,3-dihydroquinazolin-4(1H)-ones via direct cyclocondensation reaction under catalyst-free conditions
نویسندگان
چکیده
منابع مشابه
Tannic acid: A Green Catalyst for the Eco-friendly Synthesis of 2,3-dihydroquinazolin-4(1H)-ones under Solvent Free Conditions
A new, facile, cost effective, and eco-friendly protocol is reported for the synthesis of 2,3-dihydroquinazoline-4-(1H)-ones exploring tannic acid as a novel, inexpensive, andbiodegradable catalyst. A variety of dihydroquinazolins were prepared from aromatic aldehydesand anthranilamide using catalytic amount of tannic acid under solvent free conditions.Operational simplicity, high yield, and hi...
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D-tartaric acid is successfully used as a green and efficient catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones under solvent-free conditions. The developed method has many advantages, including devoid of harmful catalyst and solvents, high yield and easily work-up.
متن کاملMulticomponent reaction for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones using isatoic anhydride, aldehydes and NH4OAc under Solvent-free conditions
Quinazolinone derivatives are nowadays well recognized as valuable scaffold in drug discovery. In this manuscript an improved multicomponent process for the chemical synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives is described. Isatoic anhydride and aromatic aldehydes with ammonium acetate have been subjected to a three-component reaction under solvent-free conditions and catalysis of ...
متن کاملSulfonated Porous Carbon (SPC): An efficient and recyclable solid acid catalyst for one-pot three-component synthesis of 2,3-dihydroquinazolin-4(1H)-ones under solvent-free conditions
A simple and efficient procedure has been developed for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones derivatives under solvent-free conditions. This method uses the condensation of isatoic anhydride, aldehydes, and amines in the presence of a catalytic amount Sulfonated Porous Carbon (SPC). One of the important advantages of the new method is that the SPC could be recycled and reused.
متن کاملSulfonated Porous Carbon (SPC): An efficient and recyclable solid acid catalyst for one-pot three-component synthesis of 2,3-dihydroquinazolin-4(1H)-ones under solvent-free conditions
A simple and efficient procedure has been developed for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones derivatives under solvent-free conditions. This method uses the condensation of isatoic anhydride, aldehydes, and amines in the presence of a catalytic amount Sulfonated Porous Carbon (SPC). One of the important advantages of the new method is that the SPC could be recycled and reused.
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ژورنال
عنوان ژورنال: Green Chemistry Letters and Reviews
سال: 2015
ISSN: 1751-8253,1751-7192
DOI: 10.1080/17518253.2015.1109145